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Toshiro Fujita Selected Research

Mineralocorticoid Receptors (Mineralocorticoid Receptor)

1/2021The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury.
1/2020Two Mineralocorticoid Receptor-Mediated Mechanisms of Pendrin Activation in Distal Nephrons.
1/2019Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study.
1/2017Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension.
1/2017Hypokalemia and Pendrin Induction by Aldosterone.
1/2016Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury.
6/2015Activation of mineralocorticoid receptor in salt-sensitive hypertension.
12/2014Anti-albuminuric effect of the aldosterone blocker eplerenone in non-diabetic hypertensive patients with albuminuria: a double-blind, randomised, placebo-controlled trial.
1/2014Local mineralocorticoid receptor activation and the role of Rac1 in obesity-related diabetic kidney disease.
12/2013Aberrant Rac1-mineralocorticoid receptor pathways in salt-sensitive hypertension.
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Toshiro Fujita Research Topics

Disease

81Hypertension (High Blood Pressure)
03/2021 - 02/2002
42Proteinuria
06/2020 - 10/2001
33Hypoxia (Hypoxemia)
02/2020 - 07/2003
27Chronic Renal Insufficiency
02/2020 - 11/2002
21Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2015 - 04/2005
17Obesity
01/2021 - 07/2002
17Chronic Kidney Failure (Chronic Renal Failure)
06/2020 - 10/2002
16Insulin Resistance
10/2012 - 07/2002
15Diabetic Nephropathies (Diabetic Nephropathy)
10/2015 - 01/2002
15Ischemia
08/2011 - 02/2003
14Fibrosis (Cirrhosis)
11/2020 - 01/2002
14Inflammation (Inflammations)
06/2020 - 11/2003
13Acute Kidney Injury (Acute Renal Failure)
01/2014 - 11/2003
12Albuminuria
01/2019 - 12/2002
12Hypophosphatemia
03/2012 - 08/2002
11Cardiovascular Diseases (Cardiovascular Disease)
02/2015 - 06/2006
10Kidney Diseases (Kidney Disease)
01/2016 - 10/2006
9Glomerulonephritis
05/2011 - 01/2002
8Type 2 Diabetes Mellitus (MODY)
01/2019 - 10/2002
8Infections
02/2014 - 05/2002
8Atherosclerosis
02/2010 - 10/2000
7Diabetes Mellitus
08/2009 - 01/2002
6Heart Failure
01/2016 - 12/2002
6Hyperplasia
01/2013 - 01/2002
6Hypophosphatemic Rickets
08/2012 - 02/2004
6Nephritis
11/2011 - 01/2002
6Adenoma (Adenomas)
05/2009 - 08/2002
5Nephrosclerosis
10/2021 - 12/2007
5Nephrotic Syndrome (Syndrome, Nephrotic)
01/2019 - 12/2004
5Hyperaldosteronism (Conn Syndrome)
01/2017 - 06/2008
5Neoplasms (Cancer)
02/2014 - 05/2002
5Sclerosis
03/2012 - 11/2003
5Osteomalacia
10/2011 - 10/2009
5Thrombotic Microangiopathies
07/2006 - 10/2001
4Wounds and Injuries (Trauma)
01/2021 - 04/2009
4Hypokalemia
01/2017 - 01/2012
4Cardiomegaly (Heart Hypertrophy)
01/2016 - 03/2004
4Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia)
08/2012 - 10/2009
4Anemia
11/2011 - 12/2005
4IGA Glomerulonephritis (IGA Nephropathy)
11/2011 - 01/2009

Drug/Important Bio-Agent (IBA)

67SaltsIBA
03/2021 - 01/2002
33AldosteroneIBA
01/2021 - 06/2006
32Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
01/2021 - 02/2007
20Proteins (Proteins, Gene)FDA Link
11/2014 - 02/2002
19Angiotensin IIIBA
01/2020 - 01/2002
15Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016 - 02/2004
14Messenger RNA (mRNA)IBA
10/2015 - 02/2002
14AdrenomedullinIBA
07/2013 - 02/2003
14AntioxidantsIBA
11/2010 - 06/2003
13SodiumIBA
03/2021 - 08/2002
13NADPH Oxidases (NAD(P)H oxidase)IBA
01/2016 - 01/2002
12AlbuminsIBA
12/2014 - 05/2003
11CreatinineIBA
02/2020 - 01/2006
11Fibroblast Growth Factor-23IBA
05/2014 - 03/2004
11Glucose (Dextrose)FDA LinkGeneric
10/2012 - 07/2002
10tempolIBA
11/2018 - 12/2002
9Eplerenone (Inspra)FDA LinkGeneric
01/2016 - 06/2006
9Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2010 - 12/2004
8PotassiumIBA
01/2020 - 07/2002
81,25-dihydroxyvitamin DIBA
11/2010 - 05/2002
7Superoxide DismutaseIBA
11/2020 - 12/2002
7Antihypertensive Agents (Antihypertensives)IBA
08/2014 - 09/2004
7Phosphates (Orthophosphate)IBA
05/2014 - 02/2004
7Biomarkers (Surrogate Marker)IBA
11/2012 - 11/2007
7Parathyroid Hormone (Parathormone)IBA
10/2011 - 08/2002
7Insulin (Novolin)FDA Link
01/2011 - 07/2002
7CalciumIBA
11/2010 - 05/2002
6Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
12/2014 - 02/2003
6Angiotensin Receptor AntagonistsIBA
12/2014 - 05/2004
6Fatty Acid-Binding ProteinsIBA
02/2012 - 11/2007
6NADP (NADPH)IBA
02/2008 - 12/2002
5Epoprostenol (Prostacyclin)FDA LinkGeneric
10/2021 - 09/2014
5beraprostIBA
10/2021 - 09/2014
5Mineralocorticoid Receptor AntagonistsIBA
01/2016 - 05/2007
5Amlodipine (Norvasc)FDA LinkGeneric
01/2013 - 09/2007
5Puromycin AminonucleosideIBA
12/2011 - 12/2004
5NF-kappa B (NF-kB)IBA
11/2011 - 02/2005
5CholesterolIBA
03/2011 - 10/2002
5Losartan (Cozaar)FDA LinkGeneric
10/2008 - 09/2007
5Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
03/2008 - 02/2004
4Nitric Oxide Synthase (NO Synthase)IBA
11/2020 - 10/2001
4AngiotensinsIBA
11/2018 - 02/2004
4MineralocorticoidsIBA
01/2017 - 06/2008
4Member 3 Solute Carrier Family 12IBA
01/2017 - 05/2011
4SteroidsIBA
09/2014 - 05/2006
4DiureticsIBA
01/2014 - 09/2007
4Peptides (Polypeptides)IBA
07/2013 - 05/2004
4Monomeric GTP-Binding ProteinsIBA
02/2013 - 03/2006
4Streptozocin (Streptozotocin)FDA Link
01/2013 - 03/2004
4ReninIBA
01/2013 - 12/2005
4pimonidazoleIBA
11/2012 - 05/2004
4EnzymesIBA
09/2012 - 03/2004
4Oxidoreductases (Dehydrogenase)IBA
08/2012 - 02/2007
4Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
08/2012 - 10/2002
4LuciferasesIBA
11/2011 - 05/2006
4Oxygen (Dioxygen)IBA
11/2011 - 06/2006
4ElementsIBA
11/2011 - 12/2004

Therapy/Procedure

31Therapeutics
03/2021 - 01/2003
8Kidney Transplantation
09/2014 - 12/2009
5Peritoneal Dialysis
11/2014 - 05/2006